An Gong Niu Huang Wan: A traditional Chinese medicine for emergency treatment
An gong Niu huang Wan, also known as Peaceful Palace Bovine Bezoar Pill, is a compound Chinese medicine from traditional Chinese medicine. It is a detoxifying agent and was first mentioned in Treatise on Febrile Diseases. It is composed of a variety of precious Chinese medicinal materials and has the effects of clearing away heat and detoxifying, and refreshing the mind. It is mainly used to treat symptoms such as high fever coma, stroke coma, and pediatric syncope.
This article will introduce in detail the composition, efficacy, indications and application of Angong Niuhuang Pills in modern medicine.
Composition and production
The ingredients of Angong Niuhuang Wan include:
Bezoar: 10%
Turmeric: 10%
Coptis chinensis: 10%
Cinnabar: 10%
Mountain ash: 10%
Realgar: 10%
Scutellaria baicalensis: 10%
Rhino horn: 20%
Borneol: 2.5%
Musk: 2.5%
Pearls: 5%
Preparation method:
Pearl, cinnabar and realgar are water-melted or crushed into very fine powder.
Crush Rhizoma Coptidis, Radix Scutellariae, Fructus Corydalis, and Curcuma Radix into fine powder.
Grind bezoar, buffalo horn concentrated powder, musk and borneol into fine powder, mix with the above powder, sieve and mix well.
Add appropriate amount of refined honey to make large honey pills, and use gold foil as the coating.
Usage: Take 1 pill once a day; children under 3 years old take 1/4 pill once a day, children aged 4 to 6 years old take 1/2 pill once a day; or follow the doctor's instructions. There are also Angong Niuhuang Powder, Angong Niuhuang Capsule, and Angong Niuhuang Suppository, which can be used according to the instructions.
Pathogenesis Analysis
The pathogenesis of this prescription is that the pathogenic heat enters the pericardium, and the phlegm-heat obscures the clear orifices. When the pathogenic heat of a febrile disease is rampant and spreads to the pericardium, it will inevitably disturb the mind, resulting in high fever, irritability, coma and delirium; when the internal heat is rampant, it burns the body fluids and refines them into phlegm, and the turbid phlegm covers the clear orifices, which will inevitably aggravate the coma and delirium; the tongue is the orifice of the heart, and when the heat blocks the orifice, the tongue becomes paralyzed and speechless; when the heat is deep, the syncope is also deep, so the hands and feet of the heat syncope are accompanied. The phlegm-heat coma caused by stroke and the high fever and syncope in children treated by this prescription are also symptoms of heat closure.
Efficacy and Indications
Efficacy: The main effects of Angong Niuhuang Pills are clearing away heat and detoxification and clearing away phlegm and opening the channels. It can effectively remove heat and toxins in the body and restore consciousness by opening the channels.
Indications: Angong Niuhuang Wan is mainly used to treat the following conditions:
Febrile disease : Heat evil invades the pericardium, causing symptoms such as high fever, irritability, coma and delirium.
Stroke : Phlegm and heat block the heart, causing the heart to close, and the patient may experience symptoms such as confusion and cold limbs.
Syncope in children : Children may suffer from syncope due to phlegm-heat blocking the heart.
Modern application : In modern medicine, Angong Niuhuang Pills are also used to treat diseases caused by phlegm-heat and fainting, such as type B encephalitis, epidemic meningitis, toxic dysentery, uremia, cerebrovascular accident, toxic hepatitis, and hepatic coma.
安宮牛黃丸
Pathogenesis Analysis
Pathogenesis analysis: The composition and mechanism of action of Angong Niuhuang Wan can be analyzed from the following aspects:
King Medicine :
Bezoar : Clears the heart, detoxifies, clears phlegm and opens the channels.
Rhino horn : clears the heart, cools the blood and detoxifies.
Musk : Refreshes the mind and awakens the spirit.
Minister medicine :
Coptis chinensis, Scutellaria baicalensis, and Fructus jasminoides : clear the heat in the three burners, assist bezoar and rhinoceros horn to clear the heat in the pericardium, and enhance the effect of musk in opening the orifices and refreshing the mind.
Realgar : clears phlegm.
Adjuvant drugs :
Tulip and borneol : their fragrance can remove odor, open up the channels and clear up the blockages, and envelop the body from within.
Cinnabar, pearls, and gold foil : calm the mind and soothe the nerves.
Honey : soothes the stomach and regulates the middle, harmonizes various medicines.
Modern pharmacological research :
An gong Niu huang Wan are composed of a variety of precious Chinese medicinal materials, each of which has its own unique effects. These ingredients work together to make Angong Niuhuang Pills widely used in modern medicine.
For example, bezoar comes from the gallstones of cattle. It has the effects of clearing away heat and detoxifying, calming the nerves, and refreshing the mind. It is particularly suitable for treating patients with persistent high fever, such as Japanese encephalitis and epidemic cerebrospinal meningitis. Curcuma is a rhizome of the ginger family. It can promote blood circulation and relieve pain. Especially for stroke patients, it helps improve blood flow and reduce brain damage. Rhino horn (now replaced by buffalo horn concentrate) has the effects of clearing away heat and detoxifying, cooling blood and stopping bleeding, clearing the liver and improving eyesight. It has a significant effect on diseases such as toxic dysentery and uremia.
Coptis chinensis can remove dampness and heat from the body, and is particularly suitable for treating digestive diseases such as gastritis and dysentery. Cinnabar has the effects of clearing away heat and purging fire, calming the nerves and calming the nerves, and is particularly suitable for patients with high fever and coma. Borneol can open the mind and wake the spirit, and is particularly helpful for patients in coma due to stroke. Musk has the effects of opening the mind and activating blood circulation and removing blood stasis, and is particularly suitable for patients with pediatric syncope.
Pearl can clear away heat and detoxify, nourish yin and moisten dryness, and is particularly suitable for patients with hepatic coma. The osmanthus fragrans has the effects of clearing away heat and detoxifying, cooling blood and stopping bleeding, and is particularly suitable for patients with pulmonary encephalopathy. Realgar can detoxify and kill insects, and is particularly suitable for the treatment of infectious diseases. Scutellaria baicalensis has the effects of clearing away heat and drying dampness, purging fire and detoxifying, and is particularly suitable for patients with uremia.
An gong Niu huang Wan has anticonvulsant and antipyretic effects. It can counteract the excitatory effect of amphetamine on mice, delay the onset of pentylenetetrazol-induced convulsions in mice, and reduce convulsions and mortality. In addition, it has a significant antipyretic effect on fever in rabbits caused by bacterial toxins.
Through the above analysis, it can be seen that each ingredient in Angong Niuhuang Pills has its unique efficacy. Angong Niuhuang Pills have multiple pharmacological effects, including antioxidant, anti-intoxicant, anti-apoptosis, anti-inflammation and anti-platelet aggregation.
Diet therapy
When taking Angong Niuhuang Pills, you can also use some dietary therapy to assist in the treatment. For example:
Mung bean soup : Mung beans have the effect of clearing heat and detoxifying, which can help relieve high fever symptoms.
Lotus seed porridge : Lotus seeds have a calming effect on the nerves and can help improve the symptoms of coma and delirium.
Chrysanthemum tea : Chrysanthemum has the effects of clearing away heat and detoxifying, calming the liver and improving eyesight, and can help relieve the symptoms of high fever and coma.
Barley porridge : Barley has the effects of promoting diuresis, strengthening the spleen and stopping diarrhea, and can help improve indigestion and diarrhea.
Taboos and precautions:
Contraindications : Angong Niuhuang Wan is not suitable for stroke patients with cold and coma, otherwise it may aggravate the condition .
Note : Since it contains cinnabar and realgar, the mercuric sulfide and arsenic sulfide in these ingredients are toxic substances, so it is only suitable for emergency use and should not be taken in excess or for a long time. In addition, it is not suitable for people with impaired liver and kidney function, and pregnant women are prohibited from taking it.
Through the above analysis, it can be seen that Angong Niuhuang Wan has a significant therapeutic effect in treating pathological mechanisms such as heat evil invading the pericardium and phlegm-heat blocking the heart, and it is also widely used in modern medicine.