Liang Ge San: A TCM Formula for Clearing Heat, and Promoting Bowel Movements
- Hongji Medical
- 23 hours ago
- 4 min read
Liang Ge San, from the Song Dynasty’s Prescriptions of the Bureau of Taiping People’s Welfare Pharmacy, is a widely used traditional Chinese medicine formula. It clears heat, purges fire, and promotes bowel movements.
This formula is mainly used to treat heat-related conditions in the upper and middle parts of the body, with symptoms like chest discomfort, flushed face, dry lips, irritability, thirst, mouth sores, restlessness, sleeplessness, or delirium.

Liang Ge San Formula Explanation
The formula can be analyzed based on the roles of its ingredients: monarch, minister, assistant, and envoy.
Monarch Herb: Forsythia (Lian Qiao)Forsythia clears heat, detoxifies, reduces swelling, and disperses nodules. As the monarch herb, it primarily targets heat in the upper body, effectively clearing heat toxins and reducing swelling.
Minister Herbs: Rhubarb (Da Huang) and Mirabilite (Mang Xiao)Rhubarb and mirabilite promote bowel movements, clear heat, and reduce swelling, acting as minister herbs. Rhubarb clears accumulated heat by promoting bowel movements, allowing heat to exit through the stool. Mirabilite enhances this effect, assisting rhubarb in clearing heat and promoting bowel movements.
Assistant Herbs: Scutellaria (Huang Qin) and Gardenia (Zhi Zi)Scutellaria and gardenia clear heat, dry dampness, and detoxify, serving as assistant herbs. Scutellaria targets heat in the middle body, clearing heat toxins and drying dampness. Gardenia enhances the heat-clearing effect, addressing heat in both the middle and upper/lower body.
Envoy Herbs: Mint (Bo He), Bamboo Leaf (Dan Zhu Ye), and Licorice (Gan Cao)Mint clears the head, disperses wind-heat, and relieves symptoms in the head and face, acting as an envoy herb. Bamboo leaf clears heart heat, relieves irritability, promotes urination, and directs heat downward. Licorice harmonizes the formula, detoxifies, and protects the stomach from the formula’s cold nature, ensuring balance.

Liang Ge San Pathophysiology
Liang Ge San addresses heat accumulation in the upper and middle parts of the body, often caused by poor diet, irregular sleep, or stress in modern life.
These factors lead to heat buildup, causing symptoms like chest discomfort, flushed face, dry lips, irritability, and thirst. The formula clears heat, purges fire, and promotes bowel movements to relieve these symptoms and improve chest and stomach function.
It also targets heat toxins and upward-flaring fire, which can cause mouth sores, sore throat, or sleeplessness. Heat toxins disrupt the body’s qi and blood flow, leading to symptoms like mouth sores or sore throat.
Upward-flaring fire affects the head and face, causing flushed skin or irritability. Liang Ge San clears these heat toxins, purges fire, and promotes bowel movements to restore balance and improve qi and blood flow.
Liang Ge San Effects
The main effects of Liang Ge San include clearing heat, purging fire, and promoting bowel movements. Specific effects are:
Clearing Heat and Purging Fire: Forsythia, scutellaria, and gardenia clear heat in the upper and middle body. Forsythia targets the upper body most effectively, while scutellaria and gardenia address heat in the middle and upper/lower body.
Promoting Bowel Movements: Rhubarb and mirabilite clear heat through the stool, acting like “removing fuel from under the cauldron.”
Dispersing Wind-Heat: Mint disperses wind-heat in the upper body, relieving head and face symptoms.
Clearing Heart Irritability: Bamboo leaf clears heart heat, reduces irritability, and promotes urination to direct heat downward.
Harmonizing the Formula: Licorice balances the formula, preventing the cold herbs from harming the stomach.

Liang Ge San Indications
Liang Ge San is used for heat-related conditions in the upper and middle body, with symptoms such as:
Upper Body Heat Toxins: Flushed face, dry lips, sore throat, nosebleeds, mouth sores, swollen throat, phlegm obstruction, or thick tongue coating.
Middle Body Heat Toxins: Chest discomfort, irritability, thirst, constipation, or dark urine.
Other Symptoms: Malaria with heat, heat-induced fainting, epilepsy (with excessive heat), mania, or heat syndromes with dry tongue and constipation.
Modern Applications of Liang Ge San
Modern research shows Liang Ge San has antibacterial, anti-inflammatory, digestive, antispasmodic, pain-relieving, and antioxidant effects. It is effective for conditions like pharyngitis, stomatitis, tonsillitis, biliary infections, gallstones, acute jaundice hepatitis, and epidemic cerebrospinal meningitis.
Clinically, Liang Ge San is used for upper and middle body heat conditions and digestive issues like chronic enteritis, diarrhea, or constipation. Patients often experience significant relief from chest discomfort, flushed face, dry lips, irritability, thirst, and mouth sores after treatment.
For pharyngitis, stomatitis, or tonsillitis, Liang Ge San reduces throat pain and mouth sores. It also improves symptoms in biliary infections, gallstones, or acute jaundice hepatitis. Combined with other formulas, it effectively treats various heat-related conditions.
Liang Ge San also calms heart fire, which is common in modern life due to poor diet or pollution. Heart fire can cause irritability or sleeplessness. The formula clears heart heat, purges fire, and promotes bowel movements to relieve these symptoms and improve mental clarity.
Precautions
When using Liang Ge San, consider the following:
Stop After Bowel Movement: Discontinue use once bowel movements are achieved to avoid harming the stomach or spleen.
Caution for Pregnant or Weak Patients: Pregnant women or those with weak constitutions should use it cautiously.
Individual Differences: Adjust the formula based on the patient’s constitution, under professional guidance.
Conclusion
Liang Ge San is a versatile traditional Chinese medicine formula, ideal for treating heat-related conditions in the upper and middle body. It effectively relieves symptoms like chest discomfort, flushed face, dry lips, irritability, thirst, mouth sores, sleeplessness, and delirium by clearing heat, purging fire, and promoting bowel movements. In modern medicine, it is widely used for various heat-related and digestive conditions, showing significant clinical value.
However, it should be tailored to the individual’s constitution and used under professional guidance for optimal results. This article aims to help readers understand Liang Ge San’s origins, composition, effects, and modern applications, providing a valuable reference for clinical practice.