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Chai Hu Gui Zhi Tang: A TCM Formula for Relieving Wind-Cold Symptoms and Harmonizing Body Functions

  • Writer: Hongji Medical
    Hongji Medical
  • 12 hours ago
  • 4 min read

Chai Hu Gui Zhi Tang, a classic Chinese medicine formula from the Eastern Han Dynasty physician Zhang Zhongjing’s Treatise on Cold Damage Diseases (Shang Han Lun), is used to treat symptoms caused by wind-cold invasion affecting both the Taiyang and Shaoyang syndromes.


The Treatise on Cold Damage Diseases states: “On the sixth or seventh day of a cold-induced illness, with fever, slight chills, aching limbs, mild nausea, chest fullness, and unresolved exterior symptoms, Chai Hu Gui Zhi Tang is indicated.” This highlights its value in treating fever, chills, headaches, joint pain, mild nausea, and chest discomfort caused by wind-cold.


Chai Hu Gui Zhi Tang
Chai Hu Gui Zhi Tang
Chai Hu Gui Zhi Tang
Chai Hu Gui Zhi Tang

Chai Hu Gui Zhi Tang Formula Explanation


Chai Hu Gui Zhi Tang contains Chai Hu (Bupleurum), Gui Zhi (Cinnamon Twig), Shao Yao (Peony), Gan Cao (Licorice), Sheng Jiang (Ginger), and Da Zao (Jujube), grouped according to the "monarch, minister, assistant, and envoy" principle:


Monarch Herb: Chai HuChai Hu, the monarch herb, relieves exterior symptoms, disperses heat, and harmonizes the liver and spleen. It clears Shaoyang syndrome pathogens, promoting liver qi flow and spleen function.


Minister Herbs: Gui Zhi and Shao YaoGui Zhi and Shao Yao, the minister herbs, work together to relieve exterior cold, harmonize the body’s protective and nutritive qi, nourish blood, soothe the liver, and ease pain. They alleviate joint discomfort and regulate qi.


Assistant and Envoy Herbs: Gan Cao, Sheng Jiang, and Da ZaoGan Cao harmonizes the formula, Sheng Jiang warms the stomach and disperses cold, and Da Zao nourishes the middle and boosts qi. Together, they support digestion and enhance the formula’s overall effectiveness.


Chai Hu Gui Zhi Tang
Chai Hu Gui Zhi Tang

Chai Hu Gui Zhi Tang Pathophysiology


Chai Hu Gui Zhi Tang addresses combined Taiyang and Shaoyang syndromes caused by wind-cold invasion. Initially, wind-cold affects the Taiyang meridian, causing fever, chills, headaches, and joint pain.


If untreated or mismanaged, the pathogen progresses to the Shaoyang meridian, leading to symptoms like alternating chills and fever, chest fullness, irritability, and nausea. At this stage, Taiyang and Shaoyang syndromes coexist, making Chai Hu Gui Zhi Tang the ideal treatment.


柴胡桂枝湯
Chai Hu Gui Zhi Tang

The pathophysiology can be divided into three stages:


  • Taiyang Syndrome Stage: The early stage of wind-cold invasion affects the exterior, causing fever, chills, headaches, and joint pain. Gui Zhi Tang, a classic Taiyang treatment, relieves exterior cold and harmonizes qi.

  • Shaoyang Syndrome Stage: If untreated, the pathogen enters the Shaoyang meridian, causing alternating chills and fever, chest fullness, irritability, and nausea. Xiao Chai Hu Tang, a Shaoyang treatment, clears heat and harmonizes the liver and spleen.

  • Combined Taiyang and Shaoyang Stage: Chai Hu Gui Zhi Tang treats both syndromes simultaneously, relieving exterior and interior symptoms, harmonizing qi, and soothing the liver and spleen. Chai Hu clears Shaoyang pathogens, Gui Zhi and Shao Yao harmonize qi and relieve pain, and Gan Cao, Sheng Jiang, and Da Zao support digestion.



Indications and Effects of Chai Hu Gui Zhi Tang


Chai Hu Gui Zhi Tang is mainly used for combined Taiyang and Shaoyang symptoms, including fever, chills, headaches, joint pain, mild nausea, chest fullness, and discomfort in the chest or hypochondrium. These are typically caused by wind-cold invasion.


Chai Hu Gui Zhi Tang
Chai Hu Gui Zhi Tang

The formula combines Xiao Chai Hu Tang (for Shaoyang syndrome, clearing heat and harmonizing the liver and spleen) and Gui Zhi Tang (for Taiyang syndrome, relieving exterior cold and harmonizing qi).


Together, they address both exterior and interior symptoms, effectively relieving fever, chills, headaches, joint pain, nausea, and chest fullness. Chai Hu clears Shaoyang pathogens, Gui Zhi and Shao Yao harmonize qi and ease pain, and Gan Cao, Sheng Jiang, and Da Zao support digestion for enhanced efficacy.



Modern Applications of Chai Hu Gui Zhi Tang


In modern medicine, Chai Hu Gui Zhi Tang is widely used to treat conditions caused by wind-cold, such as fever, chills, headaches, joint pain, mild nausea, chest fullness, and hypochondrium discomfort.


It is effective for colds, influenza, pediatric tonsillitis, chronic bronchitis in the elderly, peptic ulcers, chronic gastritis, chronic pancreatitis, chronic liver and gallbladder diseases, cholecystitis, gallstones, hepatitis, pancreatitis, pleurisy, intercostal neuralgia, dizziness, and costochondritis.




Modern research confirms its ability to relieve these symptoms by addressing both exterior and interior imbalances, making it a valuable treatment for a wide range of conditions.


Precautions


When using Chai Hu Gui Zhi Tang, consider the following:

  • Syndrome Differentiation: The formula is for combined Taiyang and Shaoyang symptoms (fever, chills, headaches, joint pain, nausea, chest fullness). Ensure proper diagnosis based on symptoms and constitution for suitability.

  • Contraindications: Avoid in patients with weak constitutions, excessive sweating, or weak pulse, as it may worsen their condition.

  • Special Populations: Pregnant women, breastfeeding mothers, children, and the elderly should use it under professional guidance to ensure safety.


Conclusion


Chai Hu Gui Zhi Tang, a time-honored Chinese medicine formula, is highly effective for treating combined Taiyang and Shaoyang syndromes due to its unique composition and significant therapeutic effects.


By addressing both exterior and interior symptoms, it relieves fever, chills, headaches, joint pain, nausea, chest fullness, and hypochondrium discomfort. Its detailed origins, formula explanation, indications, effects, and modern applications highlight its importance and wide use in clinical practice. This article aims to help readers understand and apply Chai Hu Gui Zhi Tang for optimal treatment outcomes, improving patient quality of life.


 
 
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